New methods of drug delivery is the future for the pharmaceutical industry

 

The-future-of-the-pharmaceutical-industry

With the production and launch of new drugs happening all the time, attention is also very firmly focused on the delivery method of those substances to meet modern needs and requirements.

The world of technology never sits still for long, and nowhere is that more true than in the field of pharmaceuticals. With greater understanding of chronic conditions, and the focus on developing medicines that can help alleviate those conditions and their symptoms, the traditional delivery system of oral medication is not always fit for purpose. 

Step forward nanomaterials with their unique properties that can allow for implants and patches that can manage a slow steady release of drugs into the bloodstream that is proving to be a much more effective method of delivery. With the advances in the development of the electrospinning machine research in this area is now easier than ever before and is now a key focus for investment and research as the capabilities of nanomaterials are becoming more and more apparent. 

Electrospinning and electrospraying is versatile and easy to set up

The process of electrospinning or spraying in order to create nanomaterials from polymer melts and solutions is now more advanced than ever. The usability of such machines is now such that a research laboratory can be set up in a matter of months where the workforce already has some understanding of electrostatics and polymers. This means shorter lead times for getting production up and running, and upskilling the workforce is easy and quicker. All this serves to reduce costs to the business.  

Creators of electrospinning machines are able to approach the implementation at a bespoke level, ensure the set up is right for the needs and intended outcomes of the research department. This can include adapting the machinery, which comes in different varieties from small ‘proof of concept’ machines to full production. The solution is now also fully scalable, and GMP and ISO certified for pharma-grade mass production, and there are many manufacturers leading the way in this.  

The machines can use a huge variety of raw materials and natural polymers to achieve the desired output properties. From sub-micronized particles and fibers, true encapsulation, nano-in-micro particles and multi-layered core-shell structures and non-woven mesh it is possible to create powder or granules for oral (tablets, capsules, sachets), parenteral, nasal, pulmonar, ophthalmic, vaginal & topical applications and patches for transdermal, mucosal, buccal & sublingual applications. 

The benefits of electrospinning production is huge

Using these methods to create pharmaceuticals has huge benefits. Firstly the process is highly versatile. Any solvent, excipient or API (including live cells) can be used in the creation of the solutions, suspensions and emulsions used in the process, and with no stress applied on the API this guarantees a product of the highest stability and quality, as materials are produced at a molecular level ensuring virtually no defects. 

In a single step it is possible to produce a dry product with minimal moisture content and with excellent processability of final product. Dose uniformity is guaranteed, which is vital in the management of chronic conditions.  

All this lends itself to maximum potency of the final product, which is all to the benefit of the end consumer. Release of the drug is controlled and optimized allowing for a faster onset of the effects on the body, yet also minimizes side effects especially when non-oral methods of distribution are used as often side effects are the result of the drug interacting with the digestive system. 

Added to this the path to general release of a new drug can be made much easier. Of course there first needs to be the necessary data from the drug trials, but once that is available and the drug is prepared for release using certain platforms, then it makes it a lot easier to achieve market authorization. This will reduce costs of development, and there have been instances where it was possible to bring a new product to market in just one year, far quicker than you might normally expect.

Helpful Budgeting Tips for Parents with Young Children

Budget-for-Parents-with-Children

Kids are amazing, but they’re also very expensive. Even if you think you planned for the arrival of your new bundle of joy carefully, there’s a good chance that you’re going to end up with extra expenses to worry about that you never considered before.

The best thing you can do to make sure that you’re ready to deal with the various costs of young children is to build a budget. Before kids, you might not have worried too much about budgeting and preparing for every cost. However, now you’ve got more responsibilities to handle, from doctor visits to baby gear, and endless diaper costs. To make sure that you can handle the various challenges of having kids, here are some useful financial tips.

1.    Get your Budget Right

First, you need to be willing to commit to a budget that you can really get behind. Don’t just tell yourself that you’re going to watch your expenses or try and save up some extra money. Instead, track every penny you spend, and every penny that comes into your bank account from your job and other earnings. Look at how much money you’re likely to earn in the next month and design a plan for how much you’re going to allow yourself to spend.

For some people, it helps to stick to a specific budgeting philosophy. For instance, you could consider using the 50/30/20 budgeting plan. This is when you put 50% of the money that you earn towards essential bills and expenses, 30% towards your “wants” and 20% towards savings. While this option won’t work for everyone, it’s a great starting point.

2.    Work out your Lending Strategy

If you’re going to need to dip into some extra money elsewhere to afford important expenses in the coming months, then you need a lending strategy as well as a spending strategy. For instance, generally, it’s not a good idea to rack up a huge bill on your credit card if you can avoid it. Instead, it might be helpful to think about how much money you need to spend and think about taking out a short term loan instead.

This way, you’ll usually be able to benefit from lower interest rates and fewer fees to handle in the long-term. Additionally, whenever you borrow money, remember that you’ll need to update your budget to add in that extra monthly repayment.

3.    Eat at Home and Plan your Meals

One of the biggest things that people spend money on each month is food. The good news if your children are younger, is that you’re probably not going to have them asking you for meals at restaurants very often. You might not have a lot of time in your schedule to eat out regularly. However, you could be eating out more than you need to with café lunches and fast-food on an evening.

When you’re exhausted by having a career and children to look after, it often feels like a good idea to order in as much as you can. However, you’ll save a lot more money if you plan your meals in advance, make sure that they’re easy to prepare, and avoid eating outside of the home.

4.    Banish One Unnecessary Expense

When you have children, your priorities will change pretty quickly. The things that you used to think were essential won’t seem nearly as important anymore. For instance, it might be easier to choose between saving for a baby’s college fund than paying a monthly fee for a gym that you never go to.

Go through your bank statements and think about what you can get rid of that you’re not going to miss. You don’t have to give up everything, but there should be at least one unnecessary expense that you can banish. According to one recent survey, 84% of people aren’t sure how much they’re spending on monthly subscriptions. Check that you’re not paying for anything you’ve forgotten about.

5.    Constantly Adapt

Ultimately, as your children grow and your lifestyle changes, your budget will gradually become outdated and less helpful. This means that you’ll need to keep going back to your spending plan and figuring out what you can do to improve your situation.

Once every few months, arrange a night where you can sit down with your partner and figure out whether your plans are still working. Ask yourself if there’s anywhere you might be able to save or make some extra money to make your life a bit easier. Don’t forget to celebrate your little wins too. Be proud of yourself for every dollar you save.

Preparing Students for Careers of the Future: Top 10 Picks

Careers-of-the-Future:-Top-10

Going to school is one of the most important aspects of socialization that prepares people for the future. In most cases, the career or business path you follow would be influenced significantly by your interests in school. For example, the professional writers on a sites like PaperWritingPros were most likely majors in literary arts, English, or any other department that allowed them to develop an interest in essay writing. As time passed, however, there has been a paradigm shift in the correlation between education and career. This is why schools need to put in more effort in preparing students for careers of the future.

1. Prepare Technicians

Over the years, advancement in technology has cost many people their jobs. However, statistics reveal that the demand for technicians is going to increase by more than 108% in the next decade. As the demand grows, so will their annual salary. To prepare yourself, your students or children for this field, inculcate science experiments as they apply to the real-world issues.

2. Prepare Registered Nurses

Do you think the demand for nurses is already high? You have no idea that this already high demand is going to increase by another 16% within the next decade. To prepare for this, students need to see real-world applications of biology. There should be practicals that allow them to appreciate the complexity of the human body.

3. Prepare Students For Skilled Trades

The emphasis on skilled workers has increased in recent times and is projected to move even higher. The demand for electricians, welders, bricklayers, carpenters, plumbers, and other skilled workers will increase significantly in the next decade. Students need to be groomed to appreciate working with their hands rather than depending on computers all the time.

4. Prepare Heavy-Duty Drivers

Heavy-duty drivers include lorry, truck, construction, and other heavy equipment drivers. It is one of those professions that require the real-world application of mathematics. The demand for these drivers will increase significantly in the coming years.

5. Groom Physical Therapists

Statistics have shown that the demand for physical therapists will increase by at least 34% in the next five years. As a physical therapist, you can earn up to $85,000 with your professional degree. Apart from physical therapists, there will be an increase in the demand for assistants to physical therapists. There should be a lot of emphasis on hands-on biology, anatomy, and healing.

6. Prepare Web Developers

This is one of the jobs with the highest demand in the year 2019, and this demand is only going to get higher as time passes. Web developers earn a lot of money, and there isn’t any need for a specific university degree. Students who are interested in computer science and programming can be trained to start coding at an early age.

7. Prepare Writers

The rise in the demand for web developers is accompanied by a rise in the demand for writers. Students who love to write can start their writing career early by offering essay writing services to fellow students. They can also join the gig market to gain more from their profession.

8. Prepare Virtual Reality Designers

Over the years, virtual reality has been applied in several sectors from the educational sector to the health and real estate sectors. However, there is a shortage of virtual reality designers and this shortage is going to increase in the coming years.

9. Prepare Blockchain Developers

Just like the virtual reality, the proponents of blockchain technology believe that this distributed ledger technology is going to change the world during the next industrial revolution. Regular computer programmers can start learning blockchain development skills.

10. Prepare Weather Control Engineers

As global warming continues to plague the world, the need for weather control engineers is increasing. Students should learn about the negative effects of global warming and should be made to feel responsible for taking care of the environment.

 

These are the top ten jobs that would have a high demand in the future. The earlier grooming starts, the easier it will be to prepare students for these jobs.